There are several probiotic products available to relieve the symptoms of IBS; the major difference between them is the strain(s) of active bacteria they contain. The probiotics in TuZen have undergone the highest standards of scrutiny available for natural health products.
Clinical précis: Lactobacillus plantarum 299v (TuZen)
in irritable bowel syndrome (IBS)
in irritable bowel syndrome (IBS)
IIBS and the microbiome2
While the causes of IBS are still under investigation, researchers now accept that an imbalance in the gut’s microbial flora – the microbiome - is a contributing factor. Probiotics are a natural treatment option, and work by altering the ability of pathogenic bacteria to adhere to the bowel wall through several mechanisms of action:
Probiotics also secrete antimicrobial peptides and modulate the immune system.
- Creating a physical barrier
- Altering the epithelial surface glycosylation pattern
- Increasing mucin production
Probiotics also secrete antimicrobial peptides and modulate the immune system.
L. plantarum 299v (TuZen): Demonstrated relief in as many as 9 out of 10 patients with IBS3
Relief of abdominal pain and bloating.4
A study published in 2012 evaluated L. plantarum,4 one of the Lactobacillus spp. commonly found in healthy bowel mucosa.5 The authors of this randomized, double-blind, placebo-controlled trial of 214 patients with IBS concluded:
“ . . . L. plantarum 299v (DSM 9843) [TuZen] is a probiotic strain able to relieve IBS symptoms, particularly abdominal pain and bloating, in IBS patients fulfilling the Rome III criteria.”4
Study details
THESE FINDINGS ARE CONSISTENT WITH PREVIOUS CLINICAL TRIALS, WHICH REPORTED:
“ . . . L. plantarum 299v (DSM 9843) [TuZen] is a probiotic strain able to relieve IBS symptoms, particularly abdominal pain and bloating, in IBS patients fulfilling the Rome III criteria.”4
Study details
THESE FINDINGS ARE CONSISTENT WITH PREVIOUS CLINICAL TRIALS, WHICH REPORTED:
Decreased pain and flatulence.5
“The results of this study indicate that administration of Lactobacillus plantarum DSM 9843 [TuZen] with known probiotic properties decreases pain and flatulence in patients with IBS.”
Study details
Study details
Improvement in 95% of patients.3
“With regards to all IBS symptoms an improvement was noted in 95% of patients in the [TuZen] group vs 15% of patients in the placebo group (P<0.0001).”
Study details
The probiotics in TuZen have undergone the highest standards of scrutiny available for natural health products. TuZen bears Natural Product Number (NPN) 80019103.
Study details
The probiotics in TuZen have undergone the highest standards of scrutiny available for natural health products. TuZen bears Natural Product Number (NPN) 80019103.
To order TuZen, please set up an account with us
For more information,
please visit the TuZen website
please visit the TuZen website
About Ferring Natural Health
Ferring Natural Health is dedicated to exploring natural alternatives to restore the body's healthy balance. Our focus on probiotics and the human digestive system is grounded in a commitment to naturally occurring therapies supported by scientific research.TuZen®, VSL#3®, and BioGaia® are registered or licensed trademarks of Ferring Inc.
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